Prof. Stephen Tsang

Professor of Ophthalmology, Pathology & Cell Biology at Vagelos College of Physicians and Surgeons, Columbia University, USA

Prof. Stephen Tsang  specialized in Ophthalmology
Country

United States

Speciality
Ophthalmology
Subspeciality
Genetic Ophthalmology
Experience
27 years
Languages
English

Areas of expertise

  • Rare Retinal Disorders
  • Retinitis pigmentosa
  • Diabetic Retinopathy
  • Electrophysiology
  • Hereditary Retinal Degeneration
  • Macular Degeneration
  • Adult and Pediatric Genetics
  • Applied Eye Genetics
  • Eye Clinical Molecular Genetics
  • Stem Cell Transplantation

About the expert

Prof. Tsang is a prominent ophthalmologist and genetic medicine researcher at Columbia University. He has made significant contributions to the field, including generating the world's first gene-targeted model of RP and developing novel therapies. His work has led to preclinical testing of viral-gene therapy for RP. He is ranked among the top RP experts in the world and has received numerous grants and awards for his work.

Videos of the expert

    Prof. Tsang is a prominent figure in the field of ophthalmology and genetic medicine. Currently, he holds the position of Member at the Columbia Stem Cell Initiative and is a Professor of Ophthalmology, Pathology, and Cell Biology at the Vagelos College of Physicians and Surgeons, Columbia University in New York, USA.

    His educational background includes a residency in Ophthalmology at Jules Stein Eye Institute, UCLA, a medical degree (M.D.) and a Ph.D. in Genetic Medicine from Columbia University, and a Master of Philosophy (M. Phil.) in Embryonic Stem Cells from Columbia University as well. He also obtained an A.B. in Collagen Genetics from The Johns Hopkins University.

    Dr. Tsang's research focuses on retinitis pigmentosa (RP), particularly on cGMP-phosphodiesterase (PDE6) related autosomal recessive RP. He has made significant contributions to the field, including generating the world's first gene-targeted model of retinitis pigmentosa and conducting studies on PDE6 regulation of G-protein-coupled receptor signaling. His work has led to novel discoveries and preclinical testing of therapies, with viral-gene therapy being considered for clinical trials. Dr. Tsang has successfully treated preclinical models of various retinopathies and has expertise in genome engineering strategies, patient-specific knock-in models, and patient care with a precision medicine approach.

    His contributions have been widely recognized, and he is ranked among the top RP experts in the world. He has received numerous grants and research support, including the prestigious R01EY024698 and R01EY018213 from the National Institutes of Health (NIH). He has also held various positions and scientific appointments throughout his career, including serving on grant review committees, editorial boards, and advisory panels. Prof. Tsang's expertise and leadership have been sought after by organizations such as the FDA and the Medical Research Council in the UK.

    In addition to his academic and research achievements, Prof. Tsang has received several honors and awards for his contributions to the field of ophthalmology. He is an esteemed member of professional societies and has published extensively in scientific journals. Prof. Tsang's dedication to advancing the understanding and treatment of retinal diseases has made a significant impact in the field and has earned him recognition and respect from his peers.

  • Professor of Ophthalmology, Pathology & Cell Biology

    2019 - Today

    Vagelos College of Physicians and Surgeons, Columbia University, USA

  • Attending Electrophysiologist

    2004 - Today

    New York-Presbyterian Hospital

  • Associate Professor of Ophthalmology, Pathology & Cell Biology

    2011 - 2019

    Columbia University

  • Director

    2006 - 2011

    Basic Science Course in Ophthalmology

  • Assistant Professor of Pathology

    2006 - 2011

    Columbia University

  • Assistant Professor of Ophthalmology

    2003 - 2011

    Columbia University

  • Enzymology Fellow

    1999 - 2003

    Laboratory of Debora B. Farber, University of California, Los Angeles

  • House staff

    1999 - 2003

    Jules Stein Eye Institute (B.J. Mondino, Chairman), UCLA

  • Research Assistant

    1986 - 1989

    The Johns Hopkins University

  • American Board of Ophthalmology

    2005

  • Ophthalmology Residency

    Jules Stein Eye Inst., UCLA, Los Angeles, CA

    2003

  • Electrophysiology Fellowship

    Laboratories of Peter Gouras and Stephen P. Goff, Columbia University

    1999

  • Doctor of Medicine

    Columbia University, New York, NY

    1998

  • Ph.D. Genome Engineering in stem cells

    Columbia University, New York, NY

    1996

  • Editorial Board Member, International Journal of Molecular Sciences (2021)

  • Editorial Board Member, Cell and Bioscience and Taiwan Journal of Ophthalmology (2020)

  • Editorial Board Member, Orphanet Journal of Rare Diseases (2017)

  • Editorial Board Member, Nature Scientific Reports and Biomed Central Stem Cell Research & Therapy (2016)

  • Editorial Board Member, Journal of Clinical Investigation Insight (2016)

  • Fight for Sight/Grant-In-Aid Review Panel Member (2001)

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